- Trials with a EudraCT protocol (20)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
20 result(s) found for: Direct Thrombin Inhibitor.
Displaying page 1 of 1.
EudraCT Number: 2014-000388-41 | Sponsor Protocol Number: OZR-2013-27 | Start Date*: 2014-05-05 |
Sponsor Name:The Rotterdam Eye Hospital | ||
Full Title: Does oral administration of dabigatran etexilate, a direct thrombin inhibitor, achieve clinical significant concentrations of dabigatran and thrombin inhibiting activity in vitreous and subretinal ... | ||
Medical condition: Ocular accessibility of dabigatran in patients with retinal detachment | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: NL (Completed) | ||
Trial results: View results |
EudraCT Number: 2012-002263-96 | Sponsor Protocol Number: 39486 | Start Date*: 2012-07-11 |
Sponsor Name:MUMC | ||
Full Title: dabigatran and rivaroxaban: prediction of anticoagulant effect | ||
Medical condition: non valvular atrial fibrillation | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: NL (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2006-003122-28 | Sponsor Protocol Number: ArgLepi-2006 | Start Date*: 2008-12-19 | |||||||||||
Sponsor Name:Heinrich-Heine-Universität Düsseldorf | |||||||||||||
Full Title: Argatroban versus Lepirudin in Critically Ill Patients | |||||||||||||
Medical condition: Critically ill patients are usually treated with heparin for anticoagulation. A serious complication of heparin therapy is heparin-induced thrombocytopenia type II (HIT). Patients with HIT have t... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2021-000740-21 | Sponsor Protocol Number: LEX-210 | Start Date*: 2022-04-08 | |||||||||||
Sponsor Name:Octapharma AG | |||||||||||||
Full Title: Study of four-factor prothrombin complex concentrate, OCTAPLEX, in patients with acute major bleeding on direct oral anticoagulant (DOAC) therapy with factor Xa inhibitor. | |||||||||||||
Medical condition: Acute major bleeding in patients receiving DOAC therapy with factor Xa inhibitor | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Ongoing) IT (Ongoing) ES (Ongoing) AT (Ongoing) HR (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2010-018723-26 | Sponsor Protocol Number: 1160.86 | Start Date*: 2010-07-15 | |||||||||||
Sponsor Name:Boehringer Ingelheim Finland Ky | |||||||||||||
Full Title: An open label, non-comparative, pharmacokinetic and pharmacodynamic study to evaluate the effect of Dabigatran Etexilate on coagulation parameters including a calibrated thrombin time test in patie... | |||||||||||||
Medical condition: Primary VTE prevention in patients with moderate renal impairment (Creatinine Clearance 30-50 ml/min) following total hip or knee replacement surgery | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FI (Completed) AT (Completed) SE (Completed) CZ (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2004-000359-41 | Sponsor Protocol Number: D1250C00007 | Start Date*: 2004-08-31 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A Controlled, Randomised, Parallel, Multicentre Study to Assess Safety and Tolerability of the Oral Direct Thrombin Inhibitor AZD0837 in the Prevention of Stroke and other Thromboembolic Complicati... | |||||||||||||
Medical condition: Prevention of stroke and other thromboembolic complications associated with Atrial Fibrillation | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Completed) DK (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2015-001785-26 | Sponsor Protocol Number: 14-505 | Start Date*: 2016-02-15 | |||||||||||
Sponsor Name:Portola Pharmaceuticals, Inc. | |||||||||||||
Full Title: Prospective, Open-label Study of Andexanet Alfa in Patients Receiving a Factor Xa Inhibitor who Have Acute Major Bleeding (ANNEXA-4). | |||||||||||||
Medical condition: Uncontrolled bleeding in patients who have taken either a direct factor Xa inhibitor (novel oral anticoagulants) or an indirect factor Xa inhibitor (low molecular weight heparins). | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Completed) GB (Completed) BE (Completed) DE (Completed) FR (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2014-000112-33 | Sponsor Protocol Number: NL47761.041.14 | Start Date*: 2014-09-01 |
Sponsor Name:University Medical Center Utrecht | ||
Full Title: Apixaban versus antiplatelet drugs or no antithrombotic drugs after anticoagulation-associated intracerebral haemorrhage in patients with atrial fibrillation. A randomised phase II clinical trial. | ||
Medical condition: The prevention of ischaemic stroke in patients with atrial fibrillation | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: NL (Completed) | ||
Trial results: View results |
EudraCT Number: 2018-001495-38 | Sponsor Protocol Number: XYN-602 | Start Date*: 2019-02-05 | ||||||||||||||||
Sponsor Name:Xynomic Pharmaceuticals, Inc. | ||||||||||||||||||
Full Title: A Randomized, Phase 3, Double-blind, Placebo-controlled Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma | ||||||||||||||||||
Medical condition: Locally Advanced or Metastatic Renal Cell Carcinoma | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: FR (Prematurely Ended) ES (Prematurely Ended) IT (Prematurely Ended) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2004-001674-80 | Sponsor Protocol Number: ARG-E04 | Start Date*: 2005-06-13 | |||||||||||
Sponsor Name:Mitsubishi Pharma Corporation | |||||||||||||
Full Title: A Randomised, Open, Parallel Group, Multicentre Study to Examine the Safety and Effectiveness of Three Doses of Argatroban as Anticoagulant in Combination with Clopidogrel and Aspirin in Patients u... | |||||||||||||
Medical condition: Stable coronary artery disease (CAD) or unstable angina (troponin negative, i.e. within the normal range for the study site) with low to moderate anatomic risk and a requirement for elective percut... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) BE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2008-003698-42 | Sponsor Protocol Number: D1250C00012 | Start Date*: 2008-11-21 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A controlled, randomised, double-blind, double-dummy, parallel-group, phase III, multicenter study to evaluate efficacy and safety of the oral direct thrombin inhibitor AZD0837 compared to warfarin... | |||||||||||||
Medical condition: the prevention of stroke and systemic embolic events (SEE) in patients with non-valvular atrial fibrillation (AF) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Prematurely Ended) SK (Ongoing) DE (Completed) HU (Ongoing) ES (Prematurely Ended) FR (Ongoing) DK (Prematurely Ended) BG (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2007-001722-27 | Sponsor Protocol Number: D1250C00042 | Start Date*: 2007-10-11 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: Long-term treatment with the oral direct thrombin inhibitor AZD0837, compared to Vitamin-K antagonists, as stroke prevention in patients with non-valvular atrial fibrillation and one or more risk f... | |||||||||||||
Medical condition: Paroxysmal persistent or permanent non-valvular atrial fibrillation | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: HU (Suspended by CA) DK (Prematurely Ended) SE (Prematurely Ended) AT (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2009-009056-20 | Sponsor Protocol Number: 1.0 | Start Date*: 2010-01-21 | |||||||||||
Sponsor Name:MUW, Department of Clinical Pharmacology | |||||||||||||
Full Title: Does staphylothrombin enhance coagulation activation in staphylococcus aureus bacteremia? | |||||||||||||
Medical condition: Patients with staphylococci bacteremia | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: AT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2007-007536-25 | Sponsor Protocol Number: 1160.73 | Start Date*: 2008-08-26 | |||||||||||
Sponsor Name:Boehringer Ingelheim b.v. | |||||||||||||
Full Title: Randomized, Open-label study of Dabigatran Etexilate, a Novel, oral, Direct Thrombin-inhibitor in clinical development, in Elective Percutaneous Coronary Intervention. (D-Fine) | |||||||||||||
Medical condition: Acute Coronary Syndrome | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2007-002586-12 | Sponsor Protocol Number: 1160.63 | Start Date*: Information not available in EudraCT | |||||||||||
Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG | |||||||||||||
Full Title: Twice-daily oral direct thrombin inhibitor dabigatran in the long-term prevention of recurrent symptomatic venous thromboembolism in patients with symptomatic deep-vein thrombosis or pulmonary embo... | |||||||||||||
Medical condition: long-term prevention of recurrent symptomatic venous thromboembolism (VTE) in patients with symptomatic deep-vein thrombosis (DVT) or pulmonary embolism (PE) who completed 6 to 18 months of treatme... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) SE (Completed) AT (Completed) IT (Completed) PL (Completed) CZ (Completed) NL (Completed) BE (Completed) LT (Completed) LV (Completed) EE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2006-005437-38 | Sponsor Protocol Number: D1250C00008 | Start Date*: 2007-03-07 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A Controlled, Randomized, Parallel, Multicentre Study to Assess Safety and Tolerability of the Oral Direct Thrombin Inhibitor AZD0837, given as an Extended-release Formulation, in the Prevention of... | |||||||||||||
Medical condition: Paroxysmal, persistent or permanent nonvalvular atrial fibrillation | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IE (Completed) SE (Completed) HU (Completed) AT (Completed) DK (Completed) GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2004-002171-16 | Sponsor Protocol Number: BAY 59-7939 / 11528 | Start Date*: 2005-01-10 | |||||||||||
Sponsor Name:Bayer HealthCare AG | |||||||||||||
Full Title: Once-daily oral Direct Factor Xa Inhibitor BAY 59-7939 in Patients with acute symptomatic Deep Vein Thrombosis. The Einstein-DVT dose-finding study. | |||||||||||||
Medical condition: Acute syntomatic deep vein thrombosis | |||||||||||||
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Population Age: | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Completed) DK (Completed) CZ (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2011-006056-37 | Sponsor Protocol Number: 1160.143 | Start Date*: 2013-09-05 | |||||||||||
Sponsor Name:Hamilton Health Sciences Corporation | |||||||||||||
Full Title: A large, international, randomized, placebo-controlled trial to assess the impact of dabigatran (a direct thrombin inhibitor) and omeprazole (a proton-pump inhibitor) in patients suffering myocardi... | |||||||||||||
Medical condition: MINS (myocardial injury after noncardiac surgery) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) IT (Completed) PT (Completed) ES (Completed) GB (Completed) AT (Completed) DE (Prematurely Ended) CZ (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2004-001083-43 | Sponsor Protocol Number: BAY 59-7939 / 11223 | Start Date*: 2004-11-23 | |||||||||||
Sponsor Name:Bayer HealthCare AG | |||||||||||||
Full Title: Oral Direct Factor Xa Inhibitor BAY 59-7939 in Patients with acute symptomatic Deep Vein Thrombosis ODIXa-DVT A prospective, randomized, multinational, multicenter, partially blinded, parallel-grou... | |||||||||||||
Medical condition: Acute deep vein thrombosis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: HU (Completed) GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2007-001723-36 | Sponsor Protocol Number: D1250C0051 | Start Date*: 2007-10-16 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A controlled, randomized, parallel, multi-centre, feasibility study of the oral direct thrombin inhibitor AZD0837, given as extended-release formulation, in the prevention of stroke and systemic em... | |||||||||||||
Medical condition: This is a phase II study to evaluate the feasibility of conducting a study in patients with AF who are appropriate for, but unable or unwilling to take VKA therapy. The intended indication for th... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Completed) GB (Completed) DK (Completed) | |||||||||||||
Trial results: View results |
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